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Page 1
Losing the Beat: Contribution of Purkinje Cell Firing Dysfunction to Disease, and Its Reversal.
Neuroscience. 2021 May 10;462:247-261. doi: 10.1016/j.neuroscience.2020.06.008. Epub 2020 Jun 14.
Neuroscience. 2021.
PMID: 32554108
Free article.
Review.
Activation of TrkB-Akt signaling rescues deficits in a mouse model of SCA6.
Cook AA, Jayabal S, Sheng J, Fields E, Leung TCS, Quilez S, McNicholas E, Lau L, Huang S, Watt AJ.
Cook AA, et al.
Sci Adv. 2022 Sep 16;8(37):eabh3260. doi: 10.1126/sciadv.abh3260. Epub 2022 Sep 16.
Sci Adv. 2022.
PMID: 36112675
Free PMC article.
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Loss of Flocculus Purkinje Cell Firing Precision Leads to Impaired Gaze Stabilization in a Mouse Model of Spinocerebellar Ataxia Type 6 (SCA6).
Chang HHV, Cook AA, Watt AJ, Cullen KE.
Chang HHV, et al. Among authors: cook aa.
Cells. 2022 Sep 2;11(17):2739. doi: 10.3390/cells11172739.
Cells. 2022.
PMID: 36078147
Free PMC article.
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Endosomal dysfunction contributes to cerebellar deficits in spinocerebellar ataxia type 6.
Cook AA, Leung TCS, Rice M, Nachman M, Zadigue-Dube É, Watt AJ.
Cook AA, et al.
Elife. 2023 Dec 12;12:RP90510. doi: 10.7554/eLife.90510.
Elife. 2023.
PMID: 38084749
Free PMC article.
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Mitochondrial damage and impaired mitophagy contribute to disease progression in SCA6.
Leung TCS, Fields E, Rana N, Shen RYL, Bernstein AE, Cook AA, Phillips DE, Watt AJ.
Leung TCS, et al. Among authors: cook aa.
Acta Neuropathol. 2024 Jan 29;147(1):26. doi: 10.1007/s00401-023-02680-z.
Acta Neuropathol. 2024.
PMID: 38286873
Free PMC article.
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Molecular Identity and Location Influence Purkinje Cell Vulnerability in Autosomal-Recessive Spastic Ataxia of Charlevoix-Saguenay Mice.
Toscano Márquez B, Cook AA, Rice M, Smileski A, Vieira-Lomasney K, Charron F, McKinney RA, Watt AJ.
Toscano Márquez B, et al. Among authors: cook aa.
Front Cell Neurosci. 2021 Dec 14;15:707857. doi: 10.3389/fncel.2021.707857. eCollection 2021.
Front Cell Neurosci. 2021.
PMID: 34970120
Free PMC article.
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